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Difficulties of differential diagnosis in multisystem atrophy

https://doi.org/10.30629/2658-7947-2019-24-6-39-46

Abstract

Multiple systemic atrophy.(MSA) is a progressive neurodegenerative  disease with a poor prognosis and unknown etiology, which belongs to the “atypical parkinsonism” group of diseases. Currently, the diagnosis of MSA is difficult and at the present stage remains predominantly clinical. But, despite the fact that no effective treatment has been developed, timely diagnosis and symptomatic therapy can improve the patient’s quality of life. The article presents a clinical observation of a patient with MSA, a feature of which was the combination of MSA with vascular pathology, which greatly complicated and delayed the diagnosis of MSA.

About the Authors

M. P. Topuzova
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation

Mariya P. Topuzova - MD, PhD, Associate Professor of the Department of Neurology and Psychiatry, Senior Researcher of the Research Laboratory of Cerebrovascular Pathology of the Research Department of Neurology and Neurorehabilitation, V.A. Almazov Federal National Medical Research Centre.

197341, Akkuratova street 2, Saint-Petersburg.



T. M. Alekseeva
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation

197341, Akkuratova street 2, Saint-Petersburg.



А. F. Zhiryakov
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation

197341, Akkuratova street 2, Saint-Petersburg.



T. A. Pavlova
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation

197341, Akkuratova street 2, Saint-Petersburg.



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Review

For citations:


Topuzova M.P., Alekseeva T.M., Zhiryakov А.F., Pavlova T.A. Difficulties of differential diagnosis in multisystem atrophy. Russian neurological journal. 2019;24(6):39-46. (In Russ.) https://doi.org/10.30629/2658-7947-2019-24-6-39-46

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ISSN 2658-7947 (Print)
ISSN 2686-7192 (Online)