r-n-jРоссийский неврологический журналRussian neurological journal2658-79472686-7192МИА10.30629/2658-7947-2019-24-6-39-46r-n-j-45Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ И НАБЛЮДЕНИЯCLINICAL RESEARCH AND SURVEILLANCEСложности дифференциального диагноза при мультисистемной атрофииDifficulties of differential diagnosis in multisystem atrophyhttps://orcid.org/0000-0002-0175-3085ТопузоваМ. П.TopuzovaM. P.

Топузова Мария Петровна - кандидат медицинских наук, доцент кафедры неврологии и психиатрии, старший научный сотрудник НИЛ цереброваскулярной патологии НИО неврологии и нейрореабилитации.

197341, Санкт-Петербург, ул. Аккуратова, 2.

Mariya P. Topuzova - MD, PhD, Associate Professor of the Department of Neurology and Psychiatry, Senior Researcher of the Research Laboratory of Cerebrovascular Pathology of the Research Department of Neurology and Neurorehabilitation, V.A. Almazov Federal National Medical Research Centre.

197341, Akkuratova street 2, Saint-Petersburg.

topuzova_mp@almazovcentre.ruhttps://orcid.org/0000-0002-4441-1165АлексееваТ. М.AlekseevaT. M.

197341, Санкт-Петербург, ул. Аккуратова, 2.

197341, Akkuratova street 2, Saint-Petersburg.

https://orcid.org/0000-0002-8382-6523ЖиряковА. Ф.ZhiryakovА. F.

197341, Санкт-Петербург, ул. Аккуратова, 2.

197341, Akkuratova street 2, Saint-Petersburg.

https://orcid.org/0000-0002-7180-1898ПавловаТ. А.PavlovaT. A.

197341, Санкт-Петербург, ул. Аккуратова, 2.

197341, Akkuratova street 2, Saint-Petersburg.

Национальный медицинский исследовательский центр имени B.A. Алмaзoвa Министерства здравоохранения Российской ФедерацииРоссияAlmazov National Medical Research Centre of the Ministry of Health of the Russian FederationRussian Federation2019280120202463946Copyright © Топузова М.П., Алексеева Т.М., Жиряков А.Ф., Павлова Т.А., 20202020Топузова М.П., Алексеева Т.М., Жиряков А.Ф., Павлова Т.А.Topuzova M.P., Alekseeva T.M., Zhiryakov А.F., Pavlova T.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.r-n-j.com/jour/article/view/45

Multiple systemic atrophy.(MSA) is a progressive neurodegenerative  disease with a poor prognosis and unknown etiology, which belongs to the “atypical parkinsonism” group of diseases. Currently, the diagnosis of MSA is difficult and at the present stage remains predominantly clinical. But, despite the fact that no effective treatment has been developed, timely diagnosis and symptomatic therapy can improve the patient’s quality of life. The article presents a clinical observation of a patient with MSA, a feature of which was the combination of MSA with vascular pathology, which greatly complicated and delayed the diagnosis of MSA.

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The authors declare that there are no conflicts of interest present.