Epileptic manifestations of autoimmune encephalitis
https://doi.org/10.30629/2658-7947-2023-28-4-81-86
Abstract
The development of autoimmune encephalitis (AIE) is due to the formation of intracellular and extracellular neuronal antibodies to various structures of the brain tissue. Their prevalence and morbidity are comparable to infectious ones, and the detection rate has recently been increasing. Acute symptomatic seizures are an important component of the clinical core of AIE and are associated with a heterogeneous group of autoantibodies, which along with the features of the lesion topic causes a signi fi cant clinical variety of seizures. The EEG has ictal and interictal features, and the development of electrographic subclinical seizures is also possible. The basis of the treatment of AIE with epileptic seizures is immunotherapy along with the use of antiepileptic drugs with sodium channel blocking properties.
About the Authors
S. K. Yevtushenko
Donetsk National Medical University
Russian Federation
Russian Federation
Donetsk
Yu. N. Sorokin
Rostov State Medical University
Russian Federation
Russian Federation
Rostov-on-Don
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Review
For citations:
Yevtushenko S.K., Sorokin Yu.N. Epileptic manifestations of autoimmune encephalitis. Russian neurological journal. 2023;28(4):81-86. (In Russ.) https://doi.org/10.30629/2658-7947-2023-28-4-81-86
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