Аutoimmune encephalitis associated with anti-LGI-1 antibodies
https://doi.org/10.30629/2658-7947-2023-28-4-54-59
Abstract
Autoimmune encephalitis associated with anti-LGI-1 antibodies is a new type of autoimmune neurological disease.
We present a description of a clinical case — this disease in a patient who was hospitalized at the Republican Scienti fi c and Practical Center for Neurology and Neurosurgery. During the analysis of blood and cerebrospinal fl uid for the presence of antibodies to autoimmune encephalitis, antibodies — IgG to anti-LGI-1 in the blood and cerebrospinal fl uid were detected. Conducted immune therapy, including intravenous administration of glucocorticosteroids, plasmapheresis and intravenous immunoglobulin led to a pronounced positive dynamics in the patient’s condition. Follow-up data indicate that the patient returned to her previous work after a course of therapy.
About the Authors
Т. N. Charnukha
Republican Scientifi c and Practical Center of Neurology and Neurosurgery
Belarus
Belarus
Мinsk
S. А. Likhachev
Republican Scientifi c and Practical Center of Neurology and Neurosurgery
Belarus
Belarus
Мinsk
Е. А. Belahalovaya
Republican Scientifi c and Practical Center of Neurology and Neurosurgery
Belarus
Belarus
Мinsk
E. К. Sidorovich
Belarusian State Medical University
Belarus
Belarus
Мinsk
V. V. Vashсhylin
Republican Scientifi c and Practical Center of Neurology and Neurosurgery
Belarus
Belarus
Мinsk
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Review
For citations:
Charnukha Т.N., Likhachev S.А., Belahalovaya Е.А., Sidorovich E.К., Vashсhylin V.V. Аutoimmune encephalitis associated with anti-LGI-1 antibodies. Russian neurological journal. 2023;28(4):54-59. (In Russ.) https://doi.org/10.30629/2658-7947-2023-28-4-54-59
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