Clinical case of anti-NMDA receptor encephalitis associated with new coronaviral infection (COVID-19)
M. A. Khoreva,
I. Y. Serikova,
I. V. Smagina,
A. A. Golenko,
K. V. Smirnov,
A. E. Zavyalov,
I. A. Draganic https://doi.org/10.30629/2658-7947-2022-27-1-106-112
Abstract
During the outbreak of coronavirus disease 2019 (COVID-19) clinicians are increasingly involved in the observation of possible neurological complications due to the infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Some cases of encephalitis following COVID‐19 pandemic have been reported in literature that can mean possible damage to the central nervous system related to the SARS-CoV-2 infection. Early on, this was thought to be due to the direct effects of the virus itself, but the possibility of immune system mechanisms being implicated was gradually raised in scientific literature. The reports of anti‐NMDA receptor encephalitis among patients with COVID‐19 at different ages may be signs of this condition. We report the case of 16-year teenager with concomitant Anti-N-Methyl-D-Aspartate Receptor (Anti-NMDAR) encephalitis and COVID‐19. This clinical case brings arguments on the possible relationship between SARS-CoV-2 infection and autoimmune encephalitis.
About the Authors
M. A. Khoreva
Altai state medical University
Russian Federation
Russian Federation
Khoreva Marina Aleksandrovna — candidate of Medical Sciences, docent, Department of neurology and neurosurgery
Barnaul
I. Y. Serikova
Altai state medical University; Altai Regional Clinical Center for Maternal and Child Health
Russian Federation
Russian Federation
Barnaul
I. V. Smagina
Altai state medical University
Russian Federation
Russian Federation
Barnaul
A. A. Golenko
Altai Regional Clinical Center for Maternal and Child Health
Russian Federation
Russian Federation
Barnaul
K. V. Smirnov
Altai Regional Clinical Center for Maternal and Child Health
Russian Federation
Russian Federation
Barnaul
A. E. Zavyalov
Altai state medical University; Altai Regional Clinical Center for Maternal and Child Health
Russian Federation
Russian Federation
Barnaul
I. A. Draganic
Altai state medical University; Altai Regional Clinical Center for Maternal and Child Health
Russian Federation
Russian Federation
Barnaul
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Review
For citations:
Khoreva M.A., Serikova I.Y., Smagina I.V., Golenko A.A., Smirnov K.V., Zavyalov A.E., Draganic I.A. Clinical case of anti-NMDA receptor encephalitis associated with new coronaviral infection (COVID-19). Russian neurological journal. 2022;27(1):106-112. (In Russ.) https://doi.org/10.30629/2658-7947-2022-27-1-106-112
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