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Диагностика церебральной амилоидной ангиопатии: на пути к Бостонским критериям 2.0

https://doi.org/10.30629/2658-7947-2020-25-5-4-13

Полный текст:

Аннотация

В статье обсуждаются нейровизуализационные проявления церебральной амилоидной ангиопатии — заболевания, ассоциированного с долевыми внутримозговыми кровоизлияниями, конвекситальными субарахноидальными кровоизлияниями у пожилых пациентов, транзиторными фокальными неврологическими эпизодами и когнитивными расстройствами. Представлена характеристика маркеров, которые в настоящее время рассматриваются для  включения в  Бостонские диагностические  критерии 2.0. Они  представлены двумя группами: геморрагические, к которым относятся внутримозговые кровоизлияния, церебральные микрокровоизлияния, корковый поверхностный сидероз, и негеморрагические, включающие гиперинтенсивность белого вещества, пятна гиперинтенсивности белого вещества и МРТ-видимые периваскулярные пространства в полуовальном центре. Каждый из маркеров подробно описан с точки зрения патогенеза, клинических ассоциаций и проиллюстрирован.

Об авторах

О. А. Новосадова
ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава России
Россия
603005, Нижний Новгород


А. А. Кулеш
ФГБОУ ВО «Пермский государственный медицинский университет им. академика Е.А. Вагнера» Минздрава России; ГАУЗ ПК «Городская клиническая больница №4», 614107, Пермь, Россия
Россия
614000, Пермь;, 614107, Пермь


В. Н. Григорьева
ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава России
Россия
603005, Нижний Новгород


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Для цитирования:


Новосадова О.А., Кулеш А.А., Григорьева В.Н. Диагностика церебральной амилоидной ангиопатии: на пути к Бостонским критериям 2.0. Российский неврологический журнал. 2020;25(5):4-13. https://doi.org/10.30629/2658-7947-2020-25-5-4-13

For citation:


Novosadova O.A., Kulesh A.A., Grigoryeva V.N. Diagnostics of cerebral amyloid angiopathy: the way to Boston criteria 2.0. Russian neurological journal. 2020;25(5):4-13. (In Russ.) https://doi.org/10.30629/2658-7947-2020-25-5-4-13

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