Clinical case of syphilitic meningovasculitis
A. V. Safronenko,
E. V. Gantsgorn,
E. S. Postnikova,
I. M. Derzhavina,
N. V. Sukhorukova,
E. S. Danielyan,
A. V. Krishtopa https://doi.org/10.30629/2658-7947-2022-27-3-60-63
Abstract
The problem of diagnosis and treatment of the meningovascular form of neurosyphilis in neurology and clinical pharmacology has been actively discussed for over a hundred years. Invasion of pale treponema in the central nervous system occurs in the early stages of the course of syphilitic infection during the period of hematogenic dissemination of the pathogen by perforation of the vascular endothelium. With the discovery of penicillin, which is still the “standard” of syphilis treatment, neurosyphilis has become a fairly rare disease, and therefore difficulties may arise in its diagnosis. The initial phase of infection may be accompanied by an asymptomatic meningeal reaction. The article presents a clinical observation of neurosyphilis manifested by epileptic seizures and extensive ischemic stroke.
About the Authors
A. V. Safronenko
Rostov State Medical University, Department of Pharmacology and Clinical Pharmacology
Russian Federation
Russian Federation
Rostov-on-Don
E. V. Gantsgorn
Rostov State Medical University, Department of Pharmacology and Clinical Pharmacology
Russian Federation
Russian Federation
Rostov-on-Don
E. S. Postnikova
Rostov State Medical University, Department of Pharmacology and Clinical Pharmacology
Russian Federation
Russian Federation
Rostov-on-Don
I. M. Derzhavina
Hospital of the Federal Medical Institution “MSCH of the Ministry of Internal Affairs of Russia for RO”
Russian Federation
Russian Federation
Rostov-on-Don
N. V. Sukhorukova
Rostov State Medical University, Department of Pharmacology and Clinical Pharmacology
Russian Federation
Russian Federation
Rostov-on-Don
E. S. Danielyan
Rostov State Medical University, Department of Pharmacology and Clinical Pharmacology
Russian Federation
Russian Federation
Rostov-on-Don
A. V. Krishtopa
Rostov State Medical University, Department of Pharmacology and Clinical Pharmacology
Russian Federation
Russian Federation
Rostov-on-Don
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Review
For citations:
Safronenko A.V., Gantsgorn E.V., Postnikova E.S., Derzhavina I.M., Sukhorukova N.V., Danielyan E.S., Krishtopa A.V. Clinical case of syphilitic meningovasculitis. Russian neurological journal. 2022;27(3):60-63. (In Russ.) https://doi.org/10.30629/2658-7947-2022-27-3-60-63
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