r-n-jРоссийский неврологический журналRussian neurological journal2658-79472686-7192МИА10.30629/2658-7947-2024-29-6-15-19r-n-j-632Research ArticleОБЗОРЫREVIEWSСердечно-сосудистые нарушения при болезни ПаркинсонаCardiovascular disorders in Parkinson's diseasehttps://orcid.org/0000-0002-8285-9462ЮдинаВ. В.YudinaV. V.

Саратов

Saratov

dr_vera@bk.ruhttps://orcid.org/0000-0002-7330-633XВоскресенскаяО. Н.VoskresenskayaO. N.

Москва

Moscow

vos-olga@yandex.ruСаратовский государственный медицинский университет им. В.И. РазумовскогоРоссияV.I. Razumovsky Saratov State Medical UniversityRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical University (Sechenov University)Russian Federation2024250120252961519Copyright © Юдина В.В., Воскресенская О.Н., 20252025Юдина В.В., Воскресенская О.Н.Yudina V.V., Voskresenskaya O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.r-n-j.com/jour/article/view/632

Цель: проанализировать данные литературы о коморбидности сердечно-сосудистых заболеваний с болезнью Паркинсона (БП) и дать оценку роли кардиальной дизавтономии как дифференциально-диагностического критерия БП.Материал и методы. Поиск научной литературы выполнен в базах данных PubMed, ProQuest Dissertations & Theses Global, электронно-библиотечной системе издательства «Медиа Сфера» с 2014 г. по настоящее время и включает 42 релевантных источника. Методологическая предпосылка исследования — представление о дифференциально-диагностической роли автономной дисфункции в диагностике БП на премоторной стадии.Заключение. Автономная денервация сердца может возникать на премоторной стадии БП и быть ее первичным проявлением. У пациентов с БП развивается и другая коморбидная сердечно-сосудистая патология: ишемическая болезнь сердца, аритмии, кардиомиопатии и внезапная сердечная смерть. Выявление кардиальной дизавтономии важно для оказания специализированной кардиологической помощи пациентам с БП.

Objective. To review the literature data on the comorbidity of cardiovascular disease with Parkinson’s disease (PD) and to evaluate the role of cardiovascular autonomic failure as a differential diagnostic criterion for synucleinopathy. Material and methods. The search of scientific literature was performed in PubMed, ProQuest Dissertations & Theses Global databases, electronic library system of the Media Sphere publishing house from 2014 to the present and includes 42 relevant sources. The methodological premise of the study is the notion of the differentiating role of autonomic dysfunction symptoms in the diagnosis of PD at the premotor stage. Conclusion. Autonomic cardiac denervation occurs at the premotor stage of PD and may be its primary manifestations. Patients with PD also develop other comorbid cardiovascular pathology: ischaemic heart disease, arrhythmias, cardiomyopathies and sudden cardiac death. Nosological substantiation of cardiovascular autonomic failure is crucial for providing specialised cardiological care to PD patients.

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The authors declare that there are no conflicts of interest present.