r-n-jРоссийский неврологический журналRussian neurological journal2658-79472686-7192МИА10.30629/2658-7947-2023-28-6-56-61r-n-j-504Research ArticleИССЛЕДОВАНИЯ И КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL RESEARCHES AND CASE REPORTSСиндром Толосы–ХантаTolosa–Hunt syndromehttps://orcid.org/0000-0002-3785-1154КайлеваН. А.KaylevaN. A.

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https://orcid.org/0000-0001-6061-8118КулешА. А.KuleshA. A.

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aleksey.kulesh@gmail.comhttps://orcid.org/0000-0002-8350-7004СтариковаН. Л.StarikovaN. L.

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https://orcid.org/0000-0002-7536-2060КаракуловаЮ. В.KarakulovaYu. V.

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https://orcid.org/0009-0001-3489-6322ГалимшинА. Р.GalimshinA. R.

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Городская клиническая больница №4РоссияCity Clinical Hospital No. 4Russian FederationПермский государственный медицинский университет им. академика Е.А. Вагнера; Городская клиническая больница №4РоссияWagner Perm State Medical University; City Clinical Hospital No. 4Russian FederationПермский государственный медицинский университет им. академика Е.А. ВагнераРоссияWagner Perm State Medical UniversityRussian Federation2023080120242865661Copyright © Кайлева Н.А., Кулеш А.А., Старикова Н.Л., Каракулова Ю.В., Галимшин А.Р., 20242024Кайлева Н.А., Кулеш А.А., Старикова Н.Л., Каракулова Ю.В., Галимшин А.Р.Kayleva N.A., Kulesh A.A., Starikova N.L., Karakulova Y.V., Galimshin A.R.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.r-n-j.com/jour/article/view/504

Представлено описание клинического случая синдрома Толосы–Ханта (СТХ) и краткий обзор литературы. Для описанного клинического случая характерны три особенности, которым не уделялось достаточного внимания в литературе: 1) наличие за несколько лет до развития типичного эпизода СТХ рецидивирующих болей вне орбиты в сочетании с птозом без диплопии; 2) недостаточный и нестойкий клинический ответ на стандартные дозы глюкокортикоидов при высокой эффективности пульс-терапии метилпреднизолоном с последующим пероральным приемом преднизолона; 3) более длительный, чем требуется, согласно Международной классификации головных болей (ICHD-3), временной промежуток между развитием цефалалгии и появлением глазодвигательных нарушений. Данное клиническое наблюдение расширяет представления о клинической картине и лечении СТХ.

A description of a clinical case of Tolosa–Hunt syndrome (THS) and a brief review of the literature are presented. The described clinical case is characterized by three features that have not received sufficient attention in the literature: 1) the presence of recurrent pain outside the orbit in combination with ptosis without diplopia several years before the development of a typical episode of THS; 2) insufficient and unstable clinical response to standard doses of glucocorticoids with high efficiency of pulse therapy with methylprednisolone followed by oral administration of prednisolone; 3) a longer than required according to the international classification of headaches (ICHD-3) time interval between the development of cephalalgia and the appearance of oculomotor disorders. This clinical observation expands the understanding of the clinical picture and treatment of THS.

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The authors declare that there are no conflicts of interest present.