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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">r-n-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский неврологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian neurological journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2658-7947</issn><issn pub-type="epub">2686-7192</issn><publisher><publisher-name>МИА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2658-7947-2023-28-4-68-72</article-id><article-id custom-type="elpub" pub-id-type="custom">r-n-j-457</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ И НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL RESEARCH AND SURVEILLANCE</subject></subj-group></article-categories><title-group><article-title>Сложности ранней диагностики острого рассеянного энцефаломиелита</article-title><trans-title-group xml:lang="en"><trans-title>Diffi culties of early diagnosis of acute disseminated encephalomyelitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9413-3167</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебенштейн-Гумовски</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebenstein-Gumovski</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебенштейн-Гумовски М.В.</p><p> Ставрополь</p></bio><bio xml:lang="en"><p> Stavropol</p></bio><email xlink:type="simple">dr.lebenstein.g@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9187-8481</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вышлова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vyshlova</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ставрополь</p></bio><bio xml:lang="en"><p>Stavropol</p></bio><email xlink:type="simple">irisha2801@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1237-2114</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жарченко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zharchenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Ставрополь</p></bio><bio xml:lang="en"><p> Stavropol</p></bio><email xlink:type="simple">alex.zharchenko@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9858-2616</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Расуева</surname><given-names>Т. С.-М.</given-names></name><name name-style="western" xml:lang="en"><surname>Rasueva</surname><given-names>T. S.-M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Ставрополь</p></bio><bio xml:lang="en"><p> Stavropol</p></bio><email xlink:type="simple">tanzila.ross@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1472-6024</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпов</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpov</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Ставрополь</p></bio><bio xml:lang="en"><p> Stavropol</p></bio><email xlink:type="simple">Karpov25@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Ставропольский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>02</day><month>10</month><year>2023</year></pub-date><volume>28</volume><issue>4</issue><fpage>68</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лебенштейн-Гумовски М.В., Вышлова И.А., Жарченко А.В., Расуева Т.С., Карпов С.М., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Лебенштейн-Гумовски М.В., Вышлова И.А., Жарченко А.В., Расуева Т.С., Карпов С.М.</copyright-holder><copyright-holder xml:lang="en">Lebenstein-Gumovski M.V., Vyshlova I.A., Zharchenko A.V., Rasueva T.S., Karpov S.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.r-n-j.com/jour/article/view/457">https://www.r-n-j.com/jour/article/view/457</self-uri><abstract><p>К числу иммунноопосредованных заболеваний центральной нервной системы с прогрессирующей демиелинизацией относится острый рассеянный энцефаломиелит. Это заболевание протекает с развитием многообразной неврологической симптоматики, формированием очагов демиелинизации. Этиология заболевания достоверно неизвестна, однако прослеживается связь с предшествующей вирусной инфекцией. Рассмотренный в данной статье клинический случай показывает стремительное развитие заболевания с обширной демиелинизацией, формированием очагов практически во всех структурах головного мозга за короткий период времени и прогрессирующим ухудшением состояния пациента на фоне проводимой терапии.</p></abstract><trans-abstract xml:lang="en"><p>Among the in fl ammatory diseases of the central nervous system, with progressive demyelination is acute disseminated encephalomyelitis. This disease proceeds with the development of diverse neurological symptoms, the formation of foci of demyelination. The etiology of the disease is not known for certain, but there is a connection with viral diseases. The clinical case considered in this article shows the rapid development of the disease with extensive demyelination, with the formation of foci in almost all brain structures in a short period of time, and a progressive deterioration of the patient’s condition against the background of ongoing therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый рассеянный энцефаломиелит</kwd><kwd>демиелинизация</kwd><kwd>диссеминированный энцефаломиелит</kwd><kwd>менингит</kwd><kwd>рассеянный склероз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute disseminated encephalomyelitis</kwd><kwd>demyelination</kwd><kwd>disseminated encephalomyelitis</kwd><kwd>mengitis</kwd><kwd>multiple sclerosis.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hynson J.L., Kornberg A.J., Coleman L.T., Shield L., Harvey A.S., Kean M.J.. 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