r-n-jРоссийский неврологический журналRussian neurological journal2658-79472686-7192МИА10.30629/2658-7947-2022-27-2-70-75r-n-j-299Research ArticleИССЛЕДОВАНИЯ И КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL RESEARCHES AND CASE REPORTSЦереброваскулярные проявления периодической болезниCerebrovascular manifestations of familial Mediterranean feverhttps://orcid.org/0000-0003-0522-767XРаскуражевА. А.RaskurazhevA. A.

Раскуражев Антон Алексеевич – канд. мед. наук, старший научный сотрудник 1-го неврологического отделения

Москва

Anton A. Raskurazhev – MD, PhD, senior researcher, 1st neurological department Research Center of Neurology, neurologist

Moscow, Volokolamskoe shosse, h. 80.

rasckey@live.comhttps://orcid.org/0000-0002-4626-6520КузнецоваП. И.KuznetsovaP. I.

Москва

Moscow

angioneurology0@gmail.comhttps://orcid.org/0000-0002-5883-8119ТанашянМ. М.TanashyanM. M.

Москва

Moscow

mtanashyan@neurology.ruФГБНУ «Научный центр неврологии»РоссияResearch Center of NeurologyRussian Federation2022140520222727075Copyright © Раскуражев А.А., Кузнецова П.И., Танашян М.М., 20222022Раскуражев А.А., Кузнецова П.И., Танашян М.М.Raskurazhev A.A., Kuznetsova P.I., Tanashyan M.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.r-n-j.com/jour/article/view/299

Приводится обзор современных представлений о цереброваскулярных проявлениях периодической болезни (ПБ) и собственное клиническое наблюдение. Несмотря на относительную редкость нарушений мозгового кровообращения в структуре клинической феноменологии ПБ, общность многих патогенетических аспектов развития этих заболеваний указывает на необходимость детального обследования пациентов с подозрением на ПБ. Помимо этого, недостаточная информированность врачей об аутовоспалительных заболеваниях, представителем которых и является ПБ, диктует необходимость включения ПБ в спектр дифференциальной диагностики ишемического инсульта, в том числе с учетом национальных особенностей.

This article provides an overview of modern concepts of cerebrovascular manifestations of familial Mediterranean fever (FMV), also known as periodic disease, and describes own clinical observation. Despite the relative infrequency of cerebrovascular accidents in the structure of the clinical phenomenology of FMV, common pathogenetic aspects of these diseases indicate the need for a detailed examination of patients with suspected FMV. In addition, insufficient awareness of physicians about autoinflammatory diseases (of which FMV is a prominent member) underlines the need to include FMV in the spectrum of differential diagnosis of ischemic stroke, including taking into account national characteristics.

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The authors declare that there are no conflicts of interest present.