<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">r-n-j</journal-id><journal-title-group><journal-title xml:lang="ru">Российский неврологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian neurological journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2658-7947</issn><issn pub-type="epub">2686-7192</issn><publisher><publisher-name>МИА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2658-7947-2021-26-5-39-43</article-id><article-id custom-type="elpub" pub-id-type="custom">r-n-j-226</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ И НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL RESEARCH AND SURVEILLANCE</subject></subj-group></article-categories><title-group><article-title>Неврологические проявления синдрома Фара</article-title><trans-title-group xml:lang="en"><trans-title>Case of neurological manifestations of Fahr's syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8469-1635</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>Л. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>L. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><email xlink:type="simple">novicova@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8436-5610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акопян</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Akopyan</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><email xlink:type="simple">akopian@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8552-6233</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарапова</surname><given-names>К. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharapova</surname><given-names>K. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><email xlink:type="simple">harapovakarina.2020@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8105-7660</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карасева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karaseva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><email xlink:type="simple">olga-karaseva-1983@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России; &#13;
ГБУЗ РБ Больница скорой медицинской помощи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University, Ministry of Health of Russia; &#13;
SBHCI RB Emergency Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2021</year></pub-date><volume>26</volume><issue>5</issue><fpage>39</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Новикова Л.Б., Акопян А.П., Шарапова К.М., Карасева О.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Новикова Л.Б., Акопян А.П., Шарапова К.М., Карасева О.А.</copyright-holder><copyright-holder xml:lang="en">Novikova L.B., Akopyan A.P., Sharapova K.M., Karaseva O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.r-n-j.com/jour/article/view/226">https://www.r-n-j.com/jour/article/view/226</self-uri><abstract><p>Статья содержит обзор литературы, приведено наблюдение пациентки Ш., 54 года, с синдромом Фара. Авторы статьи ставили перед собой цель обратить внимание на синдром Фара, который является сферой интересов врачей разных специальностей. Повышение осведомленности врачей об этом заболевании будет способствовать его своевременной диагностике и лечению.</p></abstract><trans-abstract xml:lang="en"><p>The article contains a description of the clinical observation of a patient with Fahr’s syndrome. A review of the literature on this rare neurodegenerative disease, Fahr’s disease, and Fahr’s syndrome is presented. An observation of a 54-year-old patient Sh. with Fahr’s syndrome is presented. The authors of the article set themselves the goal of drawing attention to Fahr’s syndrome, which is the sphere of interests of doctors of various specialties. Raising the awareness of doctors about this disease will contribute to its timely diagnosis and treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь</kwd><kwd>синдром Фара</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Farah’s disease (syndrome).</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Пономарев В.В., Науменко Д.В. Болезнь Фара: клиническая картина и подходы к лечению. Журнал неврологии и психиатрии им. С.С. Корсакова. 2004;3:42–45.</mixed-citation><mixed-citation xml:lang="en">Ponomarev V.V., Naumenko D.V. Fahr’s disease: clinical presentation and treatment approaches. Journal of Neurology and Psychiatry by S.S. Korsakov. 2004;3:42–45. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Евтушенко С.К., Евтушенко И.А. Патогенез и клинические проявления ювенильной и сенильной форм болезни Фара (научный обзор). Международный неврологический журнал. 2016;1(79):159–162. )</mixed-citation><mixed-citation xml:lang="en">Yevtushenko S.K., Yevtushenko I.A. Pathogenesis and Clinical Manifestations of Juvenile and Senile Fahr Disease (Scientiﬁc Review). Mezhdunarodnyi nevrologicheskii zhurnal. 2016;1(79):159–162. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Donzuso G., Mostile G., Nicoletti A., Zappia M. Basal ganglia calciﬁcations (Fahr’s syndrome): related conditions and clinical features. Neurological Sciences. 2019;40:2251–2263. https://doi.org/10.1007/s10072-019-03998-x</mixed-citation><mixed-citation xml:lang="en">Donzuso G., Mostile G., Nicoletti A., Zappia M. Basal ganglia calciﬁcations (Fahr’s syndrome): related conditions and clinical features. Neurological Sciences. 2019;40:2251–2263. https://doi.org/10.1007/s10072-019-03998-x</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Abubakar S.A., Saidu S. Idiopathic bilateral strio-pallidodentate calcinosis (Fahr’s disease): a case report and review of the literature. Ann. Afr. Med. 2012;11(4):234–237. https://doi.org/10.4103/1596-3519.102855</mixed-citation><mixed-citation xml:lang="en">Abubakar S.A., Saidu S. Idiopathic bilateral strio-pallidodentate calcinosis (Fahr’s disease): a case report and review of the literature. Ann. Afr. Med. 2012;11(4):234–237. https://doi.org/10.4103/1596-3519.102855</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Asokan A.G., D’Souza S., Jeganathan J., Pai S. Fahr’s SyndromeAn Interesting Case Presentation. Journal of Clinical and Diagnostic Research: JCDR. 2013;7(3):532–533.</mixed-citation><mixed-citation xml:lang="en">Asokan A.G., D’Souza S., Jeganathan J., Pai S. Fahr’s SyndromeAn Interesting Case Presentation. Journal of Clinical and Diagnostic Research: JCDR. 2013;7(3):532–533.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Geschwind D.H., Loginov M., Stern J.M. Identiﬁcation of a locus on chromosome 14q for idiopathic basal ganglia calciﬁcation. Am. J. Hum. Genet. 1999;65(3):764–772. https://doi.org/10.1086/302558</mixed-citation><mixed-citation xml:lang="en">Geschwind D.H., Loginov M., Stern J.M. Identiﬁcation of a locus on chromosome 14q for idiopathic basal ganglia calciﬁcation. Am. J. Hum. Genet. 1999;65(3):764–772. https://doi.org/10.1086/302558</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">JaworskiK.,StyczyńskaM.,MandeckaM.,WaleckiJ.,KosiorD.A. Fahr syndrome: an important piece of a puzzle in the diﬀerential diagnosis of many diseases. Pol. J. Radiol. 2017;82:490–93.</mixed-citation><mixed-citation xml:lang="en">JaworskiK.,StyczyńskaM.,MandeckaM.,WaleckiJ.,KosiorD.A. Fahr syndrome: an important piece of a puzzle in the diﬀerential diagnosis of many diseases. Pol. J. Radiol. 2017;82:490–93.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Manyam B.V. What is and what is not ‘Fahr’s disease’. Parkinsonism Relat Disord. 2005;11(2):73–80.</mixed-citation><mixed-citation xml:lang="en">Manyam B.V. What is and what is not ‘Fahr’s disease’. Parkinsonism Relat Disord. 2005;11(2):73–80.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang Y., Guo X., Wu A. Association between a Novel Mutation in SLC20A2 and Familial Idiopathic Basal Ganglia Calciﬁcation. PLoS ONE. 2013;8(2):e57060. https://doi.org/10.1371/journal.pone.0057060</mixed-citation><mixed-citation xml:lang="en">Zhang Y., Guo X., Wu A. Association between a Novel Mutation in SLC20A2 and Familial Idiopathic Basal Ganglia Calciﬁcation. PLoS ONE. 2013;8(2):e57060. https://doi.org/10.1371/journal.pone.0057060</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Savino E., Soavi C., Capatti E., Borrelli M., Vigna G.B., Passaro A. et al. Bilateral strio-pallido-dentate calcinosis (Fahr’s disease): report of seven cases and revision of literature. BMC Neurology. 2016;16:165. https://doi.org/10.1186/s12883-0160693-1</mixed-citation><mixed-citation xml:lang="en">Savino E., Soavi C., Capatti E., Borrelli M., Vigna G.B., Passaro A. et al. Bilateral strio-pallido-dentate calcinosis (Fahr’s disease): report of seven cases and revision of literature. BMC Neurology. 2016;16:165. https://doi.org/10.1186/s12883-0160693-1</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Shafaq S., Haﬁz M.A., Maheen A., Shahzad A., Saleem M., Saleem A. Fahr’s syndrome: literature review of current evidence. Orphanet Journal of Rare Diseases. 2013;8:156. https://ojrd.biomedcentral.com/track/pdf/https://doi.org/10.1186/17501172-8-156</mixed-citation><mixed-citation xml:lang="en">Shafaq S., Haﬁz M.A., Maheen A., Shahzad A., Saleem M., Saleem A. Fahr’s syndrome: literature review of current evidence. Orphanet Journal of Rare Diseases. 2013;8:156. https://ojrd.biomedcentral.com/track/pdf/https://doi.org/10.1186/17501172-8-156</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Тищенко В.Н., Тищенко Г.В. Болезнь Фара при патолого-анатомическом исследовании (случай из практики). Проблемы здоровья и экологии. 2013;2(36):146–150.</mixed-citation><mixed-citation xml:lang="en">Tishchenko V.N., Tishchenko G.V. Phar Disease in pathoanatomical study (case study). Health and ecology problems. 2013;2(36):146–150. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Pistacchi M., Gioulis M., Sanson F., Marsala S.Z. Fahr’s syndrome and clinical correlation: a case series and literature review. Folia Neuropathol. 2016;54(3):282–294. https://doi.org/10.5114/fn.2016.62538(3)</mixed-citation><mixed-citation xml:lang="en">Pistacchi M., Gioulis M., Sanson F., Marsala S.Z. Fahr’s syndrome and clinical correlation: a case series and literature review. Folia Neuropathol. 2016;54(3):282–294. https://doi.org/10.5114/fn.2016.62538(3)</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Ozkara B., Ozcan M., Budak F. Fahr Syndrome with Fluctuation in Consciousness and Temporary Vision Loss. Arch. Neurol. Neurosci. 2019;5(5):13–23.</mixed-citation><mixed-citation xml:lang="en">Ozkara B., Ozcan M., Budak F. Fahr Syndrome with Fluctuation in Consciousness and Temporary Vision Loss. Arch. Neurol. Neurosci. 2019;5(5):13–23.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Goldscheider H.G., Lischewski R., Claus D., Streibl W., Waiblinger G. Clinical, endocrinological, and computerezed tomogra-</mixed-citation><mixed-citation xml:lang="en">Goldscheider H.G., Lischewski R., Claus D., Streibl W., Waiblinger G. Clinical, endocrinological, and computerezed tomography scans for symmetrical calciﬁcation of the basal ganglia. Arch. Psychiat. Nervenkr. 1980;228(1):53–65. https://doi.org/10.1007/BF00365744</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">phy scans for symmetrical calciﬁcation of the basal ganglia. Arch. Psychiat. Nervenkr. 1980;228(1):53–65. https://doi.org/10.1007/BF00365744</mixed-citation><mixed-citation xml:lang="en">Mufaddel A.A., Al-Hassani G.A. Familial idiopathic basal ganglia calciﬁcation (Fahr`s disease). Neurosciences (Riyadh). 2014;19:171–177.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Mufaddel A.A., Al-Hassani G.A. Familial idiopathic basal ganglia calciﬁcation (Fahr`s disease). Neurosciences (Riyadh). 2014;19:171–177.</mixed-citation><mixed-citation xml:lang="en">Matveeva T.V., Ovsyannikova K.S. Primary (headlight disease) and secondary calciﬁcation of the basal ganglia (clinical observation). Neurological Bulletin. 2016;XLVIII(2):57–62. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Матвеева Т.В., Овсянникова К.С. Первичная (болезнь Фара) и вторичная кальцификация базальных ганглиев (клиническое наблюдение). Неврологический вестник. 2016;XLVIII(2):57–62.</mixed-citation><mixed-citation xml:lang="en">Malyshenko Yu.A., Soroko I.V., Kober D.V., Bogachev R.S., Mityukov A.E. Pharah’s syndrome. Clinical case. Fundamental and clinical medicine. 2019;4(3):128–132. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Малышенко Ю.А., Сороко И.В., Кобер Д.В., Богачев Р.С., Митюков А.Е. Синдром Фара. Клинический случай. Фундаментальная и клиническая медицина. 2019;4(3):128–132.</mixed-citation><mixed-citation xml:lang="en">Zhou Y.Y., Yang Y., Qiu H.M. Hypoparathyroidism with Fahr’s syndrome: A case report and review of the literature. World J. Clin. Cases. 2019;7(21):3662–3670. https://doi.org/10.12998/wjcc.v7.i21.3662</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou Y.Y., Yang Y., Qiu H.M. Hypoparathyroidism with Fahr’s syndrome: A case report and review of the literature. World J. Clin. Cases. 2019;7(21):3662–3670. https://doi.org/10.12998/wjcc.v7.i21.3662</mixed-citation><mixed-citation xml:lang="en">Manyam B.V., Walters A.S., Narla K.R. Bilateral striopallidodentate calcinosis: clinical characterictics of patients seen in a registry. Mov. Disord. 2001;16:258–264.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Manyam B.V., Walters A.S., Narla K.R. Bilateral striopallidodentate calcinosis: clinical characterictics of patients seen in a registry. Mov. Disord. 2001;16:258–264.</mixed-citation><mixed-citation xml:lang="en">Nicolas G., Pottier C., Charbonnier C., Guyant-Maréchal L., Le Ber I., Pariente J. et al. French IBGC Study Group Phenotypic spectrum of probable and genetically-conﬁrmed idiopathic basal ganglia calciﬁcation. Brain. 2013;136(11):3395–3407. https://doi.org/10.1093/brain/awt255</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Nicolas G., Pottier C., Charbonnier C., Guyant-Maréchal L., Le Ber I., Pariente J. et al. French IBGC Study Group Phenotypic spectrum of probable and genetically-conﬁrmed idiopathic basal ganglia calciﬁcation. Brain. 2013;136(11):3395–3407. https://doi.org/10.1093/brain/awt255</mixed-citation><mixed-citation xml:lang="en">Hotim E.N., Zhigaltsov A.M., Appadu Kumar. The syndrome of accelerated ESR in the practice of a doctor: interpretation and tactical issues. Journal of Grodno State Medical University. 2015;1:129–133. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Хотим Е.Н., Жигальцов А.М., Аппаду Кумара. Синдром ускоренной СОЭ в практике врача: интерпретация и вопросы тактики. Журнал Гродненского государственного медицинского университета. 2015;1:129–133.</mixed-citation><mixed-citation xml:lang="en">Taylor R.B. Diﬃcult diagnosis. M: Medicine. 1992;2:592. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Dos Santos V.M., Da Mata A.M., Ribeiro K.R. Calvo I.C. Fahr’s Syndrome and Secondary Hypoparathyroidism. Rom. J. Intern. Med. 2016;54(1):63–65. https://doi.org/10.1515/rjim-2016-0007</mixed-citation><mixed-citation xml:lang="en">Dos Santos V.M., Da Mata A.M., Ribeiro K.R. Calvo I.C. Fahr’s Syndrome and Secondary Hypoparathyroidism. Rom. J. Intern. Med. 2016;54(1):63–65. https://doi.org/10.1515/rjim-2016-0007</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
