r-n-jРоссийский неврологический журналRussian neurological journal2658-79472686-7192МИА10.30629/2658-7947-2020-25-5-4-13r-n-j-115Research ArticleОБЗОРLITERATURE REVIEWДиагностика церебральной амилоидной ангиопатии: на пути к Бостонским критериям 2.0Diagnostics of cerebral amyloid angiopathy: the way to Boston criteria 2.0https://orcid.org/0000-0002-0749-3827НовосадоваО. А.NovosadovaO. A.novosadova_o_a@mail.ruhttps://orcid.org/0000-0001-6061-8118КулешА. А.KuleshA. A.aleksey.kulesh@gmail.comhttps://orcid.org/0000-0002-6256-3429ГригорьеваВ. Н.GrigoryevaV. N.vrgr@yandex.ruФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава РоссииРоссияFederal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО «Пермский государственный медицинский университет им. академика Е.А. Вагнера» Минздрава России; ГАУЗ ПК «Городская клиническая больница №4», 614107, Пермь, РоссияРоссияE.A.Vagner Perm State Medical University; City Clinical Hospital №4Russian Federation202016122020255413Copyright © Новосадова О.А., Кулеш А.А., Григорьева В.Н., 20202020Новосадова О.А., Кулеш А.А., Григорьева В.Н.Novosadova O.A., Kulesh A.A., Grigoryeva V.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.r-n-j.com/jour/article/view/115

В статье обсуждаются нейровизуализационные проявления церебральной амилоидной ангиопатии — заболевания, ассоциированного с долевыми внутримозговыми кровоизлияниями, конвекситальными субарахноидальными кровоизлияниями у пожилых пациентов, транзиторными фокальными неврологическими эпизодами и когнитивными расстройствами. Представлена характеристика маркеров, которые в настоящее время рассматриваются для  включения в  Бостонские диагностические  критерии 2.0. Они  представлены двумя группами: геморрагические, к которым относятся внутримозговые кровоизлияния, церебральные микрокровоизлияния, корковый поверхностный сидероз, и негеморрагические, включающие гиперинтенсивность белого вещества, пятна гиперинтенсивности белого вещества и МРТ-видимые периваскулярные пространства в полуовальном центре. Каждый из маркеров подробно описан с точки зрения патогенеза, клинических ассоциаций и проиллюстрирован.

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The authors declare that there are no conflicts of interest present.